Hepatitis B-Related Mononeuritis Multiplex
- 1 Department of Internal Medicine, All India Institute of Medical Sciences (AIIMS), India
- 2 Department of Pathology and Lab Medicine, All India Institute of Medical Sciences (AIIMS), India
- 3 Department of Medicine (Division of Infectious Disease), All India Institute of Medical Sciences (AIIMS), India
Abstract
HepatitisB Virus (HBV) infection can present with varied multisystem manifestationsinvolving the skin, kidneys, blood, and nervous system. We report a 57-year-oldman with HBV-related mononeuritis multiplex who had symptoms of multiplesensory-motor axonal polyneuropathies. He was evaluated for his neuropathy withnerve conduction studies and a sural nerve biopsy that revealed necrotizingsmall-vessel vasculitis. He also hadan acute liver injury. He was started on direct-acting oral antiviral therapy followed bysteroid therapy and this treatment led to the resolution of his symptoms and normalization of transaminaseswithout significant changes in nerve conduction studies at a one-year follow-up.
DOI: https://doi.org/10.3844/ajidsp.2022.54.57
Copyright: © 2022 Budha Charan Singh, Vinay N Gowda and Prasan Kumar Panda. This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Keywords
- Antiviral Therapy
- Hepatitis B Virus
- Peripheral Neuropathy
- Small-Vessel Vasculitis
- Steroid